PRIMARY GASTRIC LYMPHOMA IN A PROSPECTIVE STUDY

Authors

  • Petruta Violeta FILIP “Carol Davila” University of Medicine and Pharmacy, Bucharest
  • Sorina DIACONU “Grigore T. Popa” University of Medicine and Pharmacy Iasi, Romania
  • Paraschiva POSTOLACHE “Grigore T. Popa” University of Medicine and Pharmacy Iasi, Romania
  • Corina Silvia POP “Carol Davila” University of Medicine and Pharmacy, Bucharest

Abstract

PRIMARY GASTRIC LYMPHOMA IN A PROSPECTIVE STUDY (Abstract). Aim: To assess the of occurrence of primary gastric lymphoma using epidemiological, clinical and biological data. This rare pathology includes more different histological subtypes that can affect different segments of gastrointestinal tract. Material and methods: Retrospective analysis of the hospital-based medical records of patients with primary gastrointestinal lymphoma admitted in the Hematology Clinic of the University Emergency Hospital of Bucharest between October 2014 and June 2018. The analyzed data included demographic data, Helicobacter pylori infection, disease staging, laboratory tests and objective examination. All the patients made a CT scan of the chest, abdomen and pelvis. The histological diagnosis was based on biopsy specimens in performing upper digestive endoscopy and immunohistochemistry. All data was statistically analyzed using STATA 13 (Stata Corp LLC US). Results: This study included 21 patients that have been diagnosed with primary gastrointestinal lymphoma. It was observed that primary gastric lymphoma frequently affects more females than males. Histopathological, the majority of primary gastric lymphoma (90.41%) were B-cell lineage and diffuse large B-cell occurred in 66.66% of cases. Out of the 21 patients surveyed, 13 (61.90%) presented loss of appetite, 9 (42.85%) had abdominal pain. Anemia was present in 16 cases. Conclusions: The majority cases in our study were diffuse large B-cell lymphoma which were related to infection with Helicobacter pylori in half the cases.

Author Biographies

  • Petruta Violeta FILIP, “Carol Davila” University of Medicine and Pharmacy, Bucharest

    Faculty of Medicine
    Department of Internal Medicine III
    Emergency University Hospital, Bucharest

  • Sorina DIACONU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi, Romania

    Faculty of Medicine
    Department of Internal Medicine III
    Emergency University Hospital, Bucharest

  • Paraschiva POSTOLACHE, “Grigore T. Popa” University of Medicine and Pharmacy Iasi, Romania

    Faculty of Medicine
    Department of Medical Specialties (I)
    Clinical Rehabilitation Hospital, Iasi

  • Corina Silvia POP, “Carol Davila” University of Medicine and Pharmacy, Bucharest

    Faculty of Medicine
    Department of Internal Medicine III
    Emergency University Hospital, Bucharest

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Additional Files

Published

2019-03-29

Issue

Vol. 123 No. 1 (2019): The Medical-Surgical Journal

Section

INTERNAL MEDICINE - PEDIATRICS

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