LICHEN PLANUS PIGMENTOSUS INVERSUS IN A 67-YEAR-OLD WOMAN. CASE REPORT
Abstract
LICHEN PLANUS PIGMENTOSUS INVERSUS IN A 67-YEAR-OLD WOMAN. CASE REPORT (Abstract): Lichen planus pigmentosus inversus (LPPI) is a chronic inflammatory disorder, presenting with brown patches and macules over flexural areas. Due to its histological appearance, LPPI is believed to be a pauci-inflammatory variant of classical lichen planus. Although it is a rare disorder, its epidemiology is variable, case series being reported all over the world. Herein, we report the case of a 67-year-old woman with asymptomatic, brown to purple, macules and patches, distributed over multiple intertriginous areas. Even though current evidence suggests that LPPI is generally resistant to treatment, our patient showed improvement following topical treatment with high-potency corticosteroids. LPPI may be an under-reported disease due to misdiagnosis and it should be considered in the differential diagnosis of pigmentation over flexural areas.
References
2. Kim BS, Park KD, Chi SG, Ko HC, Lee WJ, Lee SJ, et al. Two Cases of Lichen Planus Pigmentosus-inversus Arising from Long-standing Lichen Planus-inversus. Ann Dermatol 2008; 20(4): 254-256.
3. Mohamed M, Korbi M, Hammedi F, Youssef M, Soua Y, Akkari H, et al Lichen planus pigmentosus inversus: a series of 10 Tunisian patients. Int J Dermatol 2016; 55(10): 1088-1091.
4. Chen S, Sun W, Zhou G, Chen S, Lu X. Lichen planus pigmentosus-inversus: Report of three Chinese cases and review of the published work. The Journal of Dermatology 2014; 42(1): 77-80.
5. Kanwar AJ, Dogra S, Handa S, Parsad D, Radotra BD. A study of 124 Indian patients with lichen planus pigmentosus. Clin Exp Dermatol. 2003; 28(5): 481-485.
6. Peng W-S, Tan C. Lichen planus pigmentosus-inversus following Langer's lines of cleavage: a rare clinical presentation. Dermatologica Sinica 2015; 33(4): 241-242.
7. Bennàssar A, Mas A, Julià M, Iranzo P, Ferrando J. Annular Plaques in the Skin Folds: 4 Cases of Lichen Planus Pigmentosus-Inversus. Actas Dermosifiliogr (English Edition) 2009; 100(7): 602-605.
8. Ohshima N, Shirai A, Saito I, Asahina A. Lichen planus pigmentosus-inversus occurring extensively in multiple intertriginous areas. The Journal of Dermatology 2011; 39(4): 412-414.
9. Barros HR, Almeida JRPd, Dinato SLMe, Sementilli A, Romiti N. Lichen planus pigmentosus inver-sus. An Bras Dermatol 2013; 88(6 Suppl 1): 146-149.
10. Murzaku EC, Bronsnick T, Rao BK. Axillary lichen planus pigmentosus-inversus: Dermoscopic clues of a rare entity. J Am Acad Dermatol 2014; 71(4): e119-e120.
11. Imbernón-Moya A, Churruca-Grijelmo M, Martínez-Pérez M, Lobato-Berezo A. Dermatoscopia del liquen plano pigmentado inverso. Actas Dermosifiliogr 2015; 106(10): 857-859.
12. Kashima A, Tajiri A, Yamashita A, Asada Y, Setoyama M. Two Japanese cases of lichen planus pigmentosus-inversus. Int J Dermatol 2007; 46(7): 740-742.
13. Reyes-Baraona F, Andino Navarrete R, Fich Schilcrot F. Liquen plano pigmentoso-inverso asociado a liquen plano pilaris. Piel 2014; 29(1): 336-338.
14. Matamoros E, Michelena M, Campoy MV, Teberobsky MV, Chiavassa AM. Liquen plano pigmentoso invertido asociado a virus de hepatitis C. Arch Argent Dermatol 2013; 63(2): 55-58.
15. Matos Figueredo F, Cortés Ros O, Villacrés Medina L. Liquen plano pigmentoso inverso producido por fármacos y tratado con crema de propóleos. Presentación de un caso. MediSur 2013; 11(6): 696-700.
16. Hsu C-Y, Liu D, Lee W-R, Shih Y-H. Lichen planus pigmentosus inversus caused by occupational systemic sensitization to metals in a semiconductor factory worker. Dermatitis 2017; 28(5): 324-326.
17. Kim BS, Aum JA, Kim HS, Kim SJ, Kim MB, Oh CK, et al. Coexistence of classic lichen planus and lichen planus pigmentosus-inversus: resistant to both tacrolimus and clobetasol propionate ointments. J Eur Acad Dermatol Venereol 2007; 22(1): 106-107.
18. Gaertner E, Elstein W. Lichen planus pigmentosus-inversus: case report and review of an unusual entity. Dermatol Online J 2012; 18(2): 11.
Additional Files
Published
Issue
Section
License
COPYRIGHT
Once an article is accepted for publication, MSJ requests a transfer of copyrights for published articles.
COPYRIGHT TRANSFER FORM FOR
REVISTA MEDICO-CHIRURGICALĂ A SOCIETĂȚII DE MEDICI ȘI NATURALIȘTI DIN IAȘI /
THE MEDICAL-SURGICAL JOURNAL OF THE SOCIETY OF PHYSICIANS AND NATURALISTS FROM IASI
We, the undersigned authors of the manuscript entitled
_____________________________________________________________________________________
_____________________________________________________________________________________
warrant that this manuscript, which is submitted for publication in the REVISTA MEDICO-CHIRURGICALĂ, has not been published and it is not under consideration for publication in another journal.
- we give the consent for publication in the REVISTA MEDICO-CHIRURGICALĂ, in printed and electronic format and we transfer unconditioned and complete the copyright of this manuscript to the REVISTA MEDICO-CHIRURGICALĂ, in the event of its acceptance.
- the manuscript does not break the intellectual property rights of any other person.
- we have read the submitted version of the manuscript and we are fully responsible for the content.
Names and signatures of authors / copyright owners (the following sequence is the authorship of the article):
- ______________________________/_________________________
- ______________________________/_________________________
- ______________________________/_________________________
N.B. All the authors must sign this form