FIRST YEAR OF THE COVID-19 PANDEMIC INFLUENCE ON BLADDER CANCER PATIENTS IN ONE SINGLE ACADEMIC UROLOGICAL CENTER FROM NORTH-EASTERN ROMANIA

Authors

  • D. PUIA “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • M. IVANUTA “Dr. C. I. Parhon” Clinical Hospital Iasi
  • R.F. MAMAISCHE “Dr. C. I. Parhon” Clinical Hospital Iasi
  • Andreea Elena STAN “Dr. C. I. Parhon” Clinical Hospital Iasi
  • Carina-Alexandra BANDAC “Dr. C. I. Parhon” Clinical Hospital Iasi
  • Raluca CALINIUC “Dr. C. I. Parhon” Clinical Hospital Iasi
  • C. PRICOP “Grigore T. Popa” University of Medicine and Pharmacy Iasi

DOI:

https://doi.org/10.22551/revmedchir.v125i2.2398

Abstract

The COVID-19 pandemic created an unprecedented situation who made health systems to reorganize their resources and redeploy staff away from routine diagnostic, treatment and follow‐up services. Material and methods:  have studied retrospective the medical files of bladder cancer patients referred to our clinic between 1st of March 2019- 28 of February 2020 (group A) compared with those referred between 1st of March 2020- 1st of March 2021 (group B). A total of 640 patients were included, 486 (75.94%) males and 154 (24.06%) females, aged between 22 and 92 years, with a mean age of 69.12 years (SD+/-9.62). Group A had 408 (63.75%) patients while group B 232 (36.25%). Results: We have noticed that anemia was significantly more often in group B (p=0.032), this has led to a higher necessity of preoperative blood transfusion (p=0.039) but with no differences regarding inflammatory syndrome or kidney failure incidence. Also, the hospitalization period (p=0.001) and the time from admission to surgery have been significantly shorter in group B (p=0.05). Conclusions: By trying to avoid hospitalization many patients are admitted with a poorer biological status. In addition, many bladder cancer cases will go undetected and untreated and once the pandemic has passed, we will face an excess in cancer-related mortality.

Author Biographies

  • D. PUIA, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Surgery (II)
    “Dr. C. I. Parhon” Clinical Hospital Iasi
    Department of Urology

  • M. IVANUTA, “Dr. C. I. Parhon” Clinical Hospital Iasi

    Department of Urology

  • R.F. MAMAISCHE, “Dr. C. I. Parhon” Clinical Hospital Iasi

    Department of Urology

  • Andreea Elena STAN, “Dr. C. I. Parhon” Clinical Hospital Iasi

    Department of Urology

  • Carina-Alexandra BANDAC, “Dr. C. I. Parhon” Clinical Hospital Iasi

    Department of Urology

  • Raluca CALINIUC, “Dr. C. I. Parhon” Clinical Hospital Iasi

    Department of Radiology

  • C. PRICOP, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Surgery (II)
    “Dr. C. I. Parhon” Clinical Hospital Iasi
    Department of Urology

References

1. Wu D, Wu T, Liu Q, Yang Z. The SARS-CoV-2 outbreak: What we know. Int J Infect Dis 2020; 94: 44-48 / doi: 10.1016/j.ijid.2020.03.004.
2. Hirsch JS, Ng JH, Ross DW, et al. Northwell COVID-19 Research Consortium; Northwell Nephrolo-gy COVID-19 Research Consortium. Acute kidney injury in patients hospitalized with COVID-19. Kidney Int 2020; 98(1): 209-218 / doi: 10.1016/j.kint.2020.05.006.
3. Butu A, Brumă IS, Tanasă L, et al. The Impact of COVID-19 Crisis upon the Consumer Buying Behavior of Fresh Vegetables Directly from Local Producers. Case Study: The Quarantined Area of Suceava County, Romania. Int J Environ Res Public Health. 2020; 29; 17(15): 5485 / doi: 10.3390/ijerph17155485.
4. Cumberbatch MGK, Jubber I, Black PC, et al. Epidemiology of Bladder Cancer: A Systematic Review and Contemporary Update of Risk Factors in 2018. Eur Urol 2018; 74(6): 784-795 / doi: 10.1016/j.eururo.2018.09.001.
5. EAU Guidelines Office Rapid Reaction Group: An organization-wide collaborative effort to adapt the EAU guidelines recommendations to the COVID era available at: https://uroweb.org/wp-content/uploads/Combined-oncology-COVID-19-recommendations.pdf
6. Maccagnano C, Rocchini L, Montanari E, et al. Overview of the Italian experience in surgical man-agement of bladder cancer during first month of COVID-19 pandemic. Arch Ital Urol Androl 2020; 92(4) / doi: 10.4081/aiua.2020.4.275.
7. Spencer-Bowdage S, Russell B, Rigby J, et al. The experience of UK patients with bladder cancer during the COVID-19 pandemic: a survey-based snapshot. BJU Int 2021; 127(2): 179-181 / doi: 10.1111/bju.15287.
8. Teoh JY, Ong WLK, Gonzalez-Padilla D, et al. UroSoMe Working Group. A Global Survey on the Impact of COVID-19 on Urological Services. Eur Urol 2020; 78(2): 265-275 / doi: 10.1016/ j.eururo.2020.05.025.
9. Gravas S, Bolton D, Gomez R, et al. Impact of COVID-19 on urology practice: a global perspective and snapshot analysis. Journal of Clinical Medicine 2020; 9(6): 1730.
10. Wong MCS, Fung FDH, Leung C, Cheung WWL, Goggins WB, Ng CF. The global epidemiology of bladder cancer: a Joinpoint regression analysis of its incidence and mortality trends and projection. Sci Rep 2018; 8(1): 1129 / doi: 10.1038/s41598-018-19199-z.
11. CDC COVID-19 Response Team. Severe Outcomes Among Patients with Coronavirus Disease 2019 (COVID-19) - United States, February 12-March 16, 2020. MMWR Morb Mortal Wkly Rep 2020; 69(12): 343-346 / doi: 10.15585/mmwr.mm6912e2.
12. Sutton JM. Evaluation of hematuria in adults. JAMA 1990; 263(18): 2475-2480.
13. Gonzalez AN, Lipsky MJ, Li G, et al. The Prevalence of Bladder Cancer During Cystoscopy for Asymptomatic Microscopic Hematuria. Urology. 2019; 126: 34-38 / doi: 10.1016/j.urology. 2019.01.011.
14. Wee LE, Conceicao EP, Sim XYJ, et al. Minimizing intra-hospital transmission of COVID-19: the role of social distancing. J Hosp Infect 2020; 105(2): 113-115 / doi: 10.1016/j.jhin.2020.04.016.
15. Amota O, Frunda EA, Ghirca V, et al. Urological practice during COVID-19 pandemic in Târgu Mureș. Rom J Urol 2020; 19 (1): 14-18.
16. Méjean A, Rouprêt M, Rozet F, et al. Recommendations CCAFU on the management of cancers of the urogenital system during an epidemic with Coronavirus COVID-19. Prog Urol 2020; 30(5): 221-231 / doi: 10.1016/j.purol.2020.03.009.
17. Rexer H. A study of non-muscle-invasive bladder cancer therapy : Treatment of high-grade non-muscle-invasive urothelial carcinoma of the bladder with the standard number and dosage of intravesical BCG instillations versus a reduced number intravesical BCG instillations at the standard dosage: A European Association of Urology Research Foundation randomized phase 3 study - NIMBUS - AB 37/10 of the AUO. Urologe A. 2016; 55(4): 528-531 / doi: 10.1007/s00120-016-0051-3.
18. ***Ordin Comandant acțiune Nr. 74527/23.03.2020, available at https://amf-b.ro/wp-content/ uploads /2020/04/Ordinul-74553_07.04.2020.pdf.

Additional Files

Published

2021-06-30

Issue

Vol. 125 No. 2 (2021): The Medical-Surgical Journal

Section

SURGERY

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