SURGICAL COMORBIDITIES - A HIGH MEDICAL AND FINANCIAL BURDEN FOR HEMOPHILIA CARE

Authors

  • P. SERBAN “Victor Babes” University of Medicine and Pharmacy Timisoara, Romania
  • Teodora Smaranda ARGHIRESCU Victor Babes” University of Medicine and Pharmacy Timisoara, Romania
  • Margit SERBAN Romanian Academy of Medical Sciences
  • E. BOIA “Victor Babes” University of Medicine and Pharmacy Timisoara, Romania
  • J.M. PATRASCU “Victor Babes” University of Medicine and Pharmacy Timisoara, Romania
  • Cristina Emilia URSU Romanian Academy of Medical Sciences
  • Adina TRAILA Medical Centre for Evaluation Therapy, Medical Education and Rehabilitation of Children and Young Adults, European Hemophilia Treatment Centre, Buzias, Romania
  • C. JINCA “Victor Babes” University of Medicine and Pharmacy Timisoara, Romania
  • Estera BOERIU “Victor Babes” University of Medicine and Pharmacy Timisoara, Romania
  • D. ANDREI Romanian Hemophilia Association Timisoara, Romania
  • Brigitha VLAICU Victor Babes” University of Medicine and Pharmacy Timisoara, Romania

Abstract

Comorbidity in hemophilia, a pathology non-related to the primary disease, is a relatively new chapter, catching interest along with the revolutionary improvement of the outcomes of this coagulopathy. Aim: As prophylactic replacement therapy has been only recently introduced in our country, we aimed at assessing the frequency and the medical and financial impact of the surgical life-saving interventions of some challenging comorbidities of hemophilia. Material and methods: In the frame of a retrospective observational PRO (Patient Reported Outcomes) model survey conducted on 122 persons with severe congenital coagulopathies in the period of 2019-2020, we focused our attention on surgical comorbidities compared with surgical secondary morbidity. Results: There were performed 17 surgical interventions on 16 patients, 35.95% of them being for comorbidities. The comparative analysis of the two cohorts of patients, with comorbidities versus secondary morbidity, revealed some significant discrepancies: heterogeneity of the pathologic conditions claiming surgery and the modality of its performance, emergency or elective decision. There were registered also some similarities: age of patients and quality of outcomes. What concerns the financial impact, the medical direct costs were also similar. Conclusions: Surgical comorbidities are a high medical and economic burden for hemophilia care, claiming a comprehensive analysis of their approach in order to prospectively find out the best cost-effective and cost-efficient solution on country level for these unexpected, unpredictable diseases.

Author Biographies

  • P. SERBAN, “Victor Babes” University of Medicine and Pharmacy Timisoara, Romania

    Department 14, Center for Preventive Medicine Studies

  • Teodora Smaranda ARGHIRESCU, Victor Babes” University of Medicine and Pharmacy Timisoara, Romania

    Department of Pediatrics, Division of Onco-Hematology

  • Margit SERBAN, Romanian Academy of Medical Sciences

    Onco-Hematology Research Unit, Timisoara, Romania

  • E. BOIA, “Victor Babes” University of Medicine and Pharmacy Timisoara, Romania

    Department of Pediatric Surgery

  • J.M. PATRASCU, “Victor Babes” University of Medicine and Pharmacy Timisoara, Romania

    Department of Orthopedics

  • Cristina Emilia URSU, Romanian Academy of Medical Sciences

    Onco-Hematology Research Unit, Timisoara, Romania

  • C. JINCA, “Victor Babes” University of Medicine and Pharmacy Timisoara, Romania

    Department of Pediatrics, Division of Onco-Hematology

  • Estera BOERIU, “Victor Babes” University of Medicine and Pharmacy Timisoara, Romania

    Department of Pediatrics, Division of Onco-Hematology

  • Brigitha VLAICU, Victor Babes” University of Medicine and Pharmacy Timisoara, Romania

    Department 14, Center for Preventive Medicine Studies

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Additional Files

Published

2021-06-30

Issue

Vol. 125 No. 2 (2021): The Medical-Surgical Journal

Section

PREVENTIVE MEDICINE - LABORATORY

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