• G. MARTINESCU “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Camelia Margareta BOGDĂNICI “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Irina Andreea NIAGU “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Manuela CIOCOIU “Grigore T. Popa” University of Medicine and Pharmacy Iasi


The present study aims to open a new perspective in addressing patients suffering from the dry eye syndrome through the analysis of biometric markers that explain the long-term evolution of these patients, especially those with cardiovascular dysfunctions. Material and methods: In this study were included 200 patients from Comanesti County Hospital who were examined between 2016 and 2018. The cases were structured in 4 groups of 50 patients each, with or without cardiovascular disease, with or without dry eye syndrome. Results: Gender distribution showed a slightly higher proportion of women in all study groups. Dyslipidemia was identified in 70% of patients and hypertension in 66% of them. Other frequent pathologies identified in the study group were angina pectoris which was discovered in 28% of patients and diabetes mellitus which was found in 23.3% of them.  Heart failure was found in 39% of all patients suffering from dry eye syndrome and it was significantly more frequent in women (57.5% vs. 26.7%). Conclusions: The heart failure was significantly more common in women and in those aged over 60 years for whom the estimated risk was more than 2.5 times higher in the whole group and about 2 times higher in patients suffering from the dry eye syndrome. Central corneal thickness, corneal resistance, corneal hysteresis are good predictors of the dry eye syndrome with/without cardiovascular damage.

Author Biographies

G. MARTINESCU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine

Camelia Margareta BOGDĂNICI, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine

Irina Andreea NIAGU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine

Manuela CIOCOIU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine


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