SYSTEMIC COMPLICATIONS OF CHRONIC ALCOHOL CONSUMPTION. CASE-CONTROL STUDY CORPSES VERSUS SURVIVING PATIENTS

  • D.V. CRAUCIUC “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • C.I. STAN “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • D.A. CHIRAN “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • G. STATESCU “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Anca SAVA “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Diana BULGARU-ILIESCU “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Abstract

The aim of this prospective study is to investigate the forensic cases of the Institute of Legal Medicine (ILM) Iasi compared to a group of living patients, based on chronic alcohol consumption in the past. Material and methods: The study group consisted of 120 subjects, of which 60 cadavers from ILM Iasi, alleged victims of chronic ethanol consumption, and 60 patients admitted to the Cardiology Clinic I of the “Sf. Spiridon” County Clinical Emergency Hospital from Iasi, in order to perform a case-control study. Results: The studied cases are dominated by male patients over 60 years of age, from rural areas. A cut off value of ethyl glucuronide (EtG) greater than 500 ng/ml proves to be a good predictor in the determinism of liver cirrhosis and dilated cardiomyopathy. Conclusions: Elevated levels of EtG have been shown to be a good predictor of liver cirrhosis and dilated cardiomyopathy.

Author Biographies

D.V. CRAUCIUC, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Morpho-Functional Sciences (I)

C.I. STAN, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Morpho-Functional Sciences (I)

D.A. CHIRAN, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Morpho-Functional Sciences (I)

G. STATESCU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Morpho-Functional Sciences (I)

Anca SAVA, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Morpho-Functional Sciences (I)
“Prof. Dr. N. Oblu” Emergency Clinical Hospital, Iasi, Romania
Department of Pathology

Diana BULGARU-ILIESCU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Medical Specialties (III)
Institute of Legal Medicine, Iasi, Romania

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Published
2022-06-30
Section
INTERNAL MEDICINE - PEDIATRICS