DIETARY PATTERNS IN YOUNG AND MIDDLE-AGED SUBJECTS WITH FAMILIAL HYPERCHOLESTEROLEMIA FROM NORTH-EASTERN ROMANIA

  • Alexandra MASTALERU “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Maria Magdalena LEON CONSTANTIN “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Andra OANCEA “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Elena COJOCARU “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • M. ROCA “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Irina ABDULAN “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Laura Mihaela TRANDAFIR “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • A. COSTACHE “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • F. MITU “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Abstract

Familial hypercholesterolemia (FH) is a genetic autosomal dominant disease that is characterized by very high values of low-density lipoproteins. An unbalanced diet associated with FH will increase the cardiovascular risk of fatal and non-fatal events. Material and methods: 32 patients with FH were admitted in the Cardiovascular Rehabilitation Clinic from Iasi Clinical Rehabilitation Hospital between 1st December 2020, and 31st March 2022. Dutch Lipid Clinic Network score was the instrument used for the patient’s diagnosis. Nutritional assessment was evaluated through a validated food frequency questionnaire. Results: In our study, we have observed that men diagnosed with FH eat more chicken meat, fried food, and fast food, while women have a more balanced diet, which includes vegetables and fruits. Regarding the blood tests, we noticed higher values of triglycerides and uric acid in males when compared to women. Moreover, the HDL cholesterol level was higher in women. Regardless of gender, the subjects with FH lack in eating dairy products. Conclusions: As far as we know, this is the first study that evaluates the gender-related eating habits of young and middle-aged patients with FH. The information obtained can form the framework for the implementation of active and comprehensive prevention measures in order to increase the awareness of the disease.

Author Biographies

Alexandra MASTALERU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Medical Specialties (I)
Clinical Rehabilitation Hospital, Iasi, Romania

Maria Magdalena LEON CONSTANTIN, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Medical Specialties (I)
Clinical Rehabilitation Hospital, Iasi, Romania

Andra OANCEA, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Medical Specialties (I)
Clinical Rehabilitation Hospital, Iasi, Romania

Elena COJOCARU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Morpho-Functional Sciences (I)

M. ROCA, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Medical Specialties (I)
Clinical Rehabilitation Hospital, Iasi, Romania

Irina ABDULAN, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Medical Specialties (I)

Laura Mihaela TRANDAFIR, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Mother and Child Medicine

A. COSTACHE, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Medical Specialties (I)
Clinical Rehabilitation Hospital, Iasi, Romania

F. MITU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Medical Specialties (I)
Clinical Rehabilitation Hospital, Iasi, Romania

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Published
2022-06-30
Section
INTERNAL MEDICINE - PEDIATRICS