THE ROLE OF MAXILLARY SINUS VOLUMETRY IN CHILDREN WITH OBSTRUCTIVE SLEEP APNEA
Aim: Obstructive sleep apnea (OSA) is a common sleep disorder that can also affect children and represents a risk factor for childhood developmental problems. The aim of this study was to demonstrate if there is a correlation between the maxillary sinuses and nasal airway volumes and the presence of OSA in children. Material and methods: We retrospectively analyzed 59 patients from which 28 were diagnosed with OSA and 31 were healthy patients. We calculated the total nasal airway volume and maxillary sinuses volume using a open-source software for segmentation from CBCT (cone-beam computed tomography) data. Results: There was a significant difference regarding the BMI and the maxillary sinuses volume between the OSA patients and the control group. Conclusions: The maxillary sinuses reduced volume can be used as a predictor for OSA in pediatric patients with ages between 12-18 years old.
2. Sanchez-Armengol A, Fuentes-Pradera MA, Capote-Gil F, et al. Sleep-related breathing disorders in adolescents aged 12 to 16 years: clinical and polygraphic findings. Chest 2001; 119(5): 1393-1400.
3. Kheirandish L, Gozal D. Neurocognitive dysfunction in children with sleep disorders., Dev Sci 2006; 9(4): 388-399.
4. O'Brien LM, Gozal D. Sleep in children with attention deficit/hyperactivity disorder. Minerva Pediatr. 2004; 56(6): 585-601.
5. Brouillette RT, Fernbach SK, Hunt CE. Obstructive sleep apnea in infants and children. J Pediatr 1982; 100(1): 31-40.
6. Marcus CL, Greene MG, Carroll JL. Blood pressure in children with obstructive sleep apnea. Blood pressure in children with obstructive sleep apnea. Am J Respir Crit Care Med 1988; 157(4 Pt1): 1098-1103.
7. Verhulst SL, Schrauwen N, Haentjens D, et al. Sleep-disordered breathing in overweight and obese children and adolescents: prevalence, characteristics and the role of fat distribution., Arch Dis Child 2007; 92(3): 205-208.
8. Tauman R, Ivanenko A, O'Brien LM, Gozal D. Plasma C-reactive protein levels among children with sleep-disordered breathing, Pediatrics 2004; 113(6): e564-569.
9. Fadda GL, Rosso S, Aversa S, et al. Paranasal sinuses anatomy and related diseases: a review of the anatomical variants, imaging findings and a stepwise approach to diagnosis and surgery. Surgical Ra-diologic Anatomy 2013; 35(5): 409-423.
10. Cisonni J, Lucey AD, King AJ, Islam SM, Lewis R, Goonewardene MS. Numerical simulation of pharyngeal airflow applied to obstructive sleep apnea: effect of the nasal cavity in anatomically accurate airway models, Med Biol Eng Comput 2015; 53: 1129-1139.
11. Magliulo G, Iannella G, Ciofalo A, et al. Nasal pathologies in patients with obstructive sleep apnoea, Acta Otorhinolaryngol Ital 2019; 39(4): 250-256.
12. 3D Slicer Image Computing Platform| D Slicer.[Online] March 15, 2023. https://www.slicer.org.
13. Kim YJ, Shin HK, Lee DY, Ryu JJ, Kim TH . Decreased maxillary sinus volume is a potential predictor of obstructive sleep apnea, Angle Orthod. 2020; 90(4): 556-563.
14. Rodrigues M, Gabrielli M, Junior OG, Pereira Filho V, Passeri LA. Nasal airway evaluation in ob-structive sleep apnea patients: volumetric tomography and endoscopic findings, Int J Oral Maxillofac Surg. 2017; 46: 1284-1290.
15. A. Weiglein, W. Anderhuber, G. Wolf. Radiologic anatomy of the paranasal sinuses in the child, Surg. Radiol. Anat. 1992; 14: 335-339.
16. Bhushan B, Rychlik K, Schroeder JW Jr. Development of the maxillary sinus in infants and children, Int J Pediatr Otorhinolaryngol. 2016; 91: 146-151. .
17. Lo Giudice A, Ronsivalle V, Gastaldi G, Leonardi R. Assessment of the accuracy of imaging software for 3D rendering of the upper airway, usable in orthodontic and craniofacial clinical settings, Prog Orthod. 2022; 23(1): 22.
18. Kabaliuk N, Nejati A, Loch C, et al. Strategies for Segmenting the Upper Airway in Cone-Beam Computed Tomography (CBCT) Data, Open Journal of Medical Imaging 2017; 7: 196-219.
19. Lee JH, Cho J. Sleep and Obesity., Sleep Med Clin 2022; 17(1): 111-116.
20. Haim A, Daniel S, Hershkovitz E, Goldbart AD, Tarasiuk A Obstructive sleep apnea and metabolic disorders in morbidly obese adolescents, Pediatr Pulmonol 2021; 56(12): 3983-3990.
21. Chirakalwasan N, Ruxrungtham K. The linkage of allergic rhinitis and obstructive sleep apnea, Asian Pac J Allergy Immunol. 2014; 32: 276.
22. Migueis DP, Lacerda GCB, Lopes MC, et al. Obstructive sleep apnea in patients with chronic rhi-nosinusitis with nasal polyps: a cross-sectional study, Sleep Medicine 2019; 64: 43-47.
23. Young T, Finn L, Kim H. Nasal obstruction as a risk factor for sleep-disordered breathing. The University of Wisconsin Sleep and Respiratory Research Group, J Allergy Clin Immunol. 1997; 99(2): S757-762.
24. Larsson LG, Lindberg A, Franklin KA, Lundback B. Symptoms related to obstructive sleep apnoea are common in subjects with asthma, chronic bronchitis and rhinitis in a general population, Respir Med. 2001; 95: 423-429.
25. Canova, CR et al. Increased prevalence of perennial allergic rhinitis in patients with obstructive sleep apnea, Respiration 2004; 71: 138-143.
26. Rubinstein, I. Nasal inflammation in patients with obstructive sleep apnea, Laryngoscope 1995; 105:175-177.
27. Inancli HM, Enoz M. Obstructive sleep apnea syndrome and upper airway inflammation, Recent Pat Inflamm Allergy Drug Discov. 2010; 4: 54-57.
Once an article is accepted for publication, MSJ requests a transfer of copyrights for published articles.
COPYRIGHT TRANSFER FORM FOR
REVISTA MEDICO-CHIRURGICALĂ A SOCIETĂȚII DE MEDICI ȘI NATURALIȘTI DIN IAȘI /
THE MEDICAL-SURGICAL JOURNAL OF THE SOCIETY OF PHYSICIANS AND NATURALISTS FROM IASI
We, the undersigned authors of the manuscript entitled
warrant that this manuscript, which is submitted for publication in the REVISTA MEDICO-CHIRURGICALĂ, has not been published and it is not under consideration for publication in another journal.
- we give the consent for publication in the REVISTA MEDICO-CHIRURGICALĂ, in printed and electronic format and we transfer unconditioned and complete the copyright of this manuscript to the REVISTA MEDICO-CHIRURGICALĂ, in the event of its acceptance.
- the manuscript does not break the intellectual property rights of any other person.
- we have read the submitted version of the manuscript and we are fully responsible for the content.
Names and signatures of authors / copyright owners (the following sequence is the authorship of the article):
N.B. All the authors must sign this form