THE SIGNIFICANCE OF LIFESTYLE, ASSOCIATED DISEASES, AND ANATOMICAL VARIANTS OF THE CIRCLE OF WILLIS IN THE FOR-MATION OF ANTERIOR COMMUNICATING ARTERY ANEURYSMS

Authors

  • Ana-Maria DUMITRESCU “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • L. EVA “Prof. Dr. N. Oblu” Emergency Clinical Hospital Iasi, Romania
  • Claudia Florida COSTEA “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • C.I. STAN “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • B.M. MIHAI “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Iuliana Magdalena STÂRCEA “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Cristina-Maria GAVRILESCU “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Anca SAVA “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Keywords:

CIRCLE OF WILLIS, ANTERIOR COMMUNICATING ARTERY ANEURYSM, ANATOMICAL VARIANTS, LIFESTYLE

Abstract

Intracranial aneurysm represent a cerebrovascular disease with a relatively low incidence, but among these the most common are aneurysms developed in the anterior part of the circle of Willis (CoW). Material and methods: We collected the demographic and morphological data of the patients admitted in “Prof. Dr. N. Oblu” Emergency Clinical Hospital, Iași, Romania, with ruptured AcomA aneurysms, who later deceased and were autopsied in the Pathology Department of the same hospital, over a period of 6 years (January 2014 to December 2019), and analyzed data related to: age, gender, lifestyle (heavy smoking and alcoholism), type of anatomical variant of circle of Willis, and presence of any associated diseases. Results: We identified 7 patients with ruptured AComA aneurysm. 57.14% were male patients. The average age was 60.85 (range 34 to 69). Left posterior communicating artery (PcomA) was hypoplastic in 100% of all deceased patients. Right PComA presented hypoplasia (71.42%) or fetal type variant (28.57%). 71.42% of all cases showed anatomical variants both in the anterior and the posterior part of CoW. 66% of the female patients with AComA aneurysm presented obesity, type 2 diabetes, atherosclerotic disease and hypertension. 100% of male patients presented hypertension and atherosclerotic disease, 75% of them were chronic alcohol consumers and 50% were heavy smokers. Conclusions: The lifestyle, associated diseases, and anatomical variants of the component arteries of the circle of Willis, both from its anterior and posterior parts, could be risk factors for the formation of anterior communicating artery aneurysm.

Author Biographies

  • Ana-Maria DUMITRESCU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Morpho-Functional Sciences (I)

  • L. EVA, “Prof. Dr. N. Oblu” Emergency Clinical Hospital Iasi, Romania

    2nd Clinic of Neurosurgery

  • Claudia Florida COSTEA, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Surgery (II)

  • C.I. STAN, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Morpho-Functional Sciences (I)

  • B.M. MIHAI, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Medical Specialties (II)

  • Iuliana Magdalena STÂRCEA, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Mother and Child Medicine

  • Cristina-Maria GAVRILESCU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Medical Specialties (II)

  • Anca SAVA, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Morpho-Functional Sciences (I)
    “Prof. Dr. N. Oblu” Emergency Clinical Hospital Iasi, Romania
    Department of Pathology

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Additional Files

Published

2023-06-30

Issue

Vol. 127 No. 2 (2023): The Medical-Surgical Journal

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BASIC SCIENCES

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