URTICARIA IN CHILDREN - A DISEASE IN DISGUISE

Authors

  • Alice Nicoleta AZOICAI “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Ileana Katerina IONIUC “Sf. Maria'” Emergency Clinical Hospital for Children, Iasi

Abstract

Urticaria is considered a multifactorial condition, initializing or triggering chronic conditions with dermal or/and hypodermic localization, more common in children and young people. Material and methods: A number of 87 children were considered in a retrospective study aiming the diagnostic of acute and chronic urticaria, evolutive particularities and immunological aspects of the allergic condition. Descriptive analysis and correlation with biological parameters of the immunological status (total IgE, allergen-specific Ig E IgA, IgM, IgG) were performed. Results: The age distribution showed that most children aged 10-15, with a balanced gender distribution (59.57% male vs. 40.43% female patients). Immunological profile associated immune deficiency (IgA and IgG, a minority of patients presenting deficiency of IgM). Elevation of IgE values were found in 9% of cases. Low serum levels of Ig G, A, and M associated clinical features such as upper respiratory infection, gastroenteritis, and otitis media. Four patients with multiple immunoglobulin deficiency and 5 cases with single immunoglobulin deficiency were noticed, including a complete IgA deficiency. Arthritic impairment was observed in 10% of cases. Conclusions: Various immune deficiencies were found in children with acute and chronic urticaria. Prospective research is needed to clarify the real role of triggers in the pathogenesis of urticaria and their relative prevalence, in order to apply, with greater accuracy, prevention methods in children at risk.

Author Biographies

  • Alice Nicoleta AZOICAI, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Maternal and Child Medicine

  • Ileana Katerina IONIUC, “Sf. Maria'” Emergency Clinical Hospital for Children, Iasi

    IInd Pediatric Clinic

References

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Additional Files

Published

2023-09-30

Issue

Vol. 127 No. 3 (2023): The Medical-Surgical Journal

Section

INTERNAL MEDICINE - PEDIATRICS

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