COMORBIDITIES OF AUTOIMMUNE BULLOUS DERMATOSES IN NORTH-EASTERN ROMANIA
Abstract
Autoimmune bullous dermatoses (ABDs) are associated with a variety of systemic comorbidities, determined either by skin pathology or by the effects of systemic corticosteroid treatment. The most important comorbidities encountered in autoimmune bullous dermatoses belong to the cardiovascular, neurological, psychiatric, metabolic or infectious sphere. Materials and methods: We performed a retrospective observational study used the Minimum Basic Data Set of hospital discharges to review records of patients admitted to Sf Spiridon Iasi public hospital between 2015 and 2019 with a diagnosis of any autoimmune bullous disorder. The objectives were to describe the triggering factors and the comorbidity profile of patients with autoimmune bullous dermatoses. Results: The study included 225 patients, the most common autoimmune bullous dermatosis being pemphigus vulgaris. Some comorbidities, diabetes mellitus, or high blood pressure are more often found in patients with bullous pemphigoid, while vulgar pemphigus is more commonly associated with other diseases of autoimmune etiology (autoimmune thyroiditis, vitiligo). Conclusions: Evaluation of triggering factors and comorbidities before starting treatment may assist in controlling the disease more swiftly and reducing the side effects of treatment in the management of ABDs.
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