BREAST FIBROADENOMAS: ULTRASOUND APPEARANCE AND POTENTIAL ASSOCIATION WITH PERIPHERAL VEIN THROMBOSIS
Abstract
The aim of this study was to characterize the ultrasound appearance of breast fibroadenomas and explore a potential association with peripheral vein thrombosis. Materials and methods: We retrospectively studied between January 2021 and December 2022 the imaging records and reports of 159 women with fibroadenomas who underwent breast ultrasound (US) with an 11-18 MHz linear transducer and 7 of them lower extremity US for suspicion of peripheral vein thrombosis with an 11-18 MHz linear or a 3-6 MHz curved transducer. Results: We found a total of 293 fibroadenomas, and the most frequent pattern was: isoechoic (69.62% lesions), homogenous (77.47% lesions), with well-defined (100%), macrolobulated margins (51.88%), oval-shaped (95.22% tumors), with a Solbiati index greater than or equal to 2 (51.19%), without Doppler signal (73.72%). We studied the correlation between the Doppler signal and contour pattern, the number of lobulations, and the Solbiati index using a function in Python, and we found the following results: the dimensions of the fibroadenoma (r = 0.117438) and the number of lobulations (r = 0.282) have a positive correlation, but the Solbiati index (r = -0.012) and contour pattern (r = -0.243945) have a negative correlation with the presence of the Doppler signal. The association of multiple breast fibroadenomas with peripheral vein thrombosis was rare (7.46% cases). We monitored 147 patients with simple fibroadenomas every six months for two years, and none of them had a significant variation in the dimensions. Conclusions: The association of multiple breast fibroadenomas with peripheral vein thrombosis was rare, so we considered it to be a random association. In our study, the most frequent pattern of fibroadenomas was isoechoic, homogenous, oval-shaped lesions with macrolobulated margins, a Solbiati index greater than or equal to 2, and no Doppler signal. According to our experience, we offered, for typical fibroadenomas, the option of conservative management. A fine needle biopsy was advised in one case with atypical-appearance lesions at ultrasound.
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