TESTICULAR TUMORS IN PEDIATRIC POPULATION: SINGLE CENTER EXPERIENCE

Authors

  • O. BÎCĂ Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • I. SÂRBU Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Diana BENCHIA Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Ș. POPA Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Ludmila LOZNEANU Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Carmen-Iulia CIONGRADI Grigore T. Popa” University of Medicine and Pharmacy Iasi

Abstract

Our study aims to provide valuable contributions to the understanding and management of this rare condition, with a particular focus on our single-center experience and analysis of cases in light of limited worldwide reports. Materials and methods: This study analyzed 18 patients between 2003 and 2023. We categorized patients into two age groups: prepubertal (ages 0-11 yrs.) and postpubertal (ages 12- 18 yrs.), based on the typical onset of puberty in males, in order to compare distinct tumor characteristics. We assessed clinical data, staging imaging, pre-operative serum tumor marker values, surgical approaches, chemotherapy protocols, and clinical outcomes. Results: There was no significant difference in the prevalence of the different types of clinical presentations between groups. The overall survival (OS) rate was 94.4%, while the progression free survival (PFS) was 77.8%. The postpubertal age group had a significantly lower PFS period compared to patients in the prepubertal age group. Conclusions: This research highlights the importance of precisely performing physical, imaging, and biological tests for the early detection of testicular cancer. It emphasizes the significance of ongoing research and collaborative efforts to enhance testicular cancer management.

Author Biographies

  • O. BÎCĂ, Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Surgery (II)

  • I. SÂRBU, Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Surgery (II)

  • Diana BENCHIA, Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Surgery (II)

  • Ș. POPA, Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Surgery (II)

  • Ludmila LOZNEANU, Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Morpho-Functional Sciences (I)

  • Carmen-Iulia CIONGRADI, Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Surgery (II)

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Additional Files

Published

2024-09-18