PARTIAL SPLENIC EMBOLIZATION-MINIMALLY INVASIVE ALTERNATIVE TO SURGICAL SPLENECTOMY IN THROMBOCYTOPENIC HYPERSPLENISM. A SINGLE CENTER EXPERIENCE

Authors

  • O. ZARA “St. John” Emergency Hospital, Bucharest, Romania
  • Claudia IACOBESCU “St. John” Emergency Hospital, Bucharest, Romania
  • Valeria GRIGORESCU “St. John” Emergency Hospital, Bucharest, Romania
  • Alice Lavinia BALACEANU St. John” Emergency Hospital, Bucharest, Romania
  • Maria NEDELCU “Carol Davila” University of Medicine and Pharmacy, Bucharest
  • I. DINA “St. John” Emergency Hospital, Bucharest, Romania

DOI:

https://doi.org/10.22551/1psdrc07

Abstract

Partial splenic embolization (PSE) is a minimally invasive procedure that replaced radical surgical intervention of splenectomy for the treatment of severe cytopenia, mainly life-threatening thrombocytopenia secondary to hypersplenism in advanced liver disease. Materials and methods: This is an observational, retrospective and analytical study of 15 patients undergoing PSE from “St. John” Emergency Hospital Bucharest, admitted to Gastroenterology Clinic for several complications of liver cirrhosis, during May 2013-July 2019, while the patients’ survival rate was followed up until November 2024. Results: Our results confirm once again that PSE is a reliable nonsurgical technique used to improve the consequences of hypersplenism associated with portal hypertension in chronic liver disease, especially in liver cirrhosis. Generally, the postembolization course was uneventful; non-severe complications developed and were properly managed by conservative treatment. Conclusions: A significant improvement of platelet number was obtained in all patients, allowing better outcome for each case, especially if a surgical intervention is scheduled.

Author Biographies

  • O. ZARA, “St. John” Emergency Hospital, Bucharest, Romania

    Cardiology Clinic

  • Claudia IACOBESCU, “St. John” Emergency Hospital, Bucharest, Romania

    Gastroenterology Clinic 

  • Valeria GRIGORESCU, “St. John” Emergency Hospital, Bucharest, Romania

    Gastroenterology Clinic 

  • Alice Lavinia BALACEANU, St. John” Emergency Hospital, Bucharest, Romania

    Internal Medicine Clinic
    “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania

  • I. DINA, “St. John” Emergency Hospital, Bucharest, Romania

    Gastroenterology Clinic
    “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania

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Additional Files

Published

2025-07-08

Issue

Vol. 129 No. 2 (2025): The Medical-Surgical Journal

Section

SURGERY

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