PERINATAL PROFILE OF INFANTS DIAGNOSED WITH CONGENITAL HEART DISEASE: A HOSPITAL-BASED COHORT STUDY

Authors

  • Petra-Caroline MAYAYA Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania
  • Raluca Ozana CHISTOL Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania
  • Laura Mihaela TRANDAFIR Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania
  • Otilia Elena FRĂSINARIU Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania
  • Elena HANGANU Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania
  • G. C. MOROȘAN Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania
  • Anca BIVOLEANU Cuza-Vodă Clinical Hospital of Obstetrics and Gynecology Iasi, Romania
  • G. C. MOROȘAN Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania
  • Cristina FURNICĂ Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania

DOI:

https://doi.org/10.22551/MSJ.2026.02.08

Abstract

Congenital heart disease (CHD) is the most common congenital anomaly worldwide and remains associated with significant neonatal morbidity. Perinatal factors such as prematurity and low birth weight may influence immediate clinical outcomes. This study aimed to describe the perinatal characteristics of children diagnosed with CHD in a level I regional hospital. Materials and methods: This retrospective descriptive study included children with confirmed CHD diagnosed between 2017-2023. CHD cases were classified into left-to-right shunt lesions, right-to-left shunt lesions, obstructive malformations, and complex CHD. Extracted perinatal variables included sex, gestational age, prematurity categories, birth weight, Apgar scores at 1 and 5 minutes, and mode of delivery. Data are presented as mean ± SD or number (percentage). Results: A total of 138 children were included, 50.72% of whom were male. The mean gestational age was 36.37±2.75weeks, with 49 (35.51%) born preterm. Mean birth weight was 2692.55 ± 865.11 g, and low birth weight was observed in 50 (36.23%). Cesarean delivery occurred in 80 (60.10%) of cases. The highest proportions of CHD subtype were observed for complex lesions (28.99%) and right-to-left shunt defects (30.43%). Conclusions: This cohort demonstrates a notable burden of prematurity and reduced birth weight in the context of a high proportion of hemodynamically significant CHD. These findings underscore the importance of coordinated perinatal care and highlight the value of regional epidemiological data for informed healthcare planning.

Author Biographies

  • Raluca Ozana CHISTOL, Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania

    Prof. Dr. George I. M. Georgescu Cardiovascular Diseases Institute, Iasi, Romania

  • Laura Mihaela TRANDAFIR, Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania

    Sf. Maria Emergency Clinical Hospital for Children Iasi, Romania

  • Otilia Elena FRĂSINARIU, Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania

    Sf. Maria Emergency Clinical Hospital for Children Iasi, Romania

  • Elena HANGANU, Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania

    Sf. Maria Emergency Clinical Hospital for Children Iasi, Romania

  • G. C. MOROȘAN, Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania

    Cuza-Vodă Clinical Hospital of Obstetrics and Gynecology Iasi, Romania

  • G. C. MOROȘAN, Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania

    Institute of Forensic Medicine, Iasi, Romania

  • Cristina FURNICĂ, Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania

    Institute of Forensic Medicine, Iasi, Romania

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Additional Files

Published

2026-06-01

Issue

Section

INTERNAL MEDICINE - PEDIATRICS