QUALITY OF LIFE IN CROHN’S DISEASE PATIENTS
Abstract
The aim of the study is to assess the impact of Crohn’s Disease (CD) on quality of life (QoL) patients with and to identify the significant modifications in QoL, depending on both the development particularities of CD and the epidemiologic parameters. Material and methods: a prospective study was conducted at the Institute of Gastroenterology and Hepathology Iași, between October 2011 and August 2014. The study enrolled 63 patients with CD. The CD diagnosis was based on clinical, biological, endoscopic and histological criteria. QoL was assessed by means of the IBDQ-32 questionnaire (Inflammatory Bowel Disease Questionnaire). Results: The total IBDQ score varied from 70 to 200, registering a slightly higher value in female patients. Parameters such as age, sex and smoking/ non-smoking status did not present significant differences in the IBDQ score. The values of the IBDQ score were in indirect, mild correlation with the CDAI score; over 49% of the subjects with higher CDAI had a lower IBDQ score. Conclusions: Except for the disease activity periods, the results of the studies investigating the impact of the various factors on the QoL in patients with CD are contradictory. Further research is needed in order to define the subgroups of patients likely to suffer from poorer QoL.
References
2. Andrews J.M. et al. Review article: Un-promoted issues in inflammatory bowel disease: opportunities to optimize care Intern Med J 2010; 40: 173–182.
3. Pizzi LT, Weston CM, Goldfarb NI et al. Impact of chronic conditions on quality of life in patients with inflammatory bowel disease. Inflamm Bowel Dis 2006; 12: 47–52.
4. Mnif L, Mzid A, Amouri A, Chtourou L, Tahri N. Health-related quality of life in patients with in-flammatory bowel disease: a Tunisian study. Tunis Med; 2010; 88:933-936.
5. Ebrahim S., Clinical and public health perspectives and applications of health-related quality of life measurement. Soc Sci Med 1995; 41(10): 1383-1394.
6. Sajid MS, Rimpel J, Iftikhar M. Use of health related quality of life tools in colorectal surgery. Acta Chir Belg 2007; 107(6): 623-629.
7. Guyatt G, Mitcell A, Irvine EJ, Singer J. Et al. A new measure of health status for clinical trials in inflammatory bowel disease. Gastroenterol 1989; 96: 804-810.
8. Zhou Y, Ren W, Irvine EJ, Yang D. Assessing health-related quality of life in patients with inflamma-tory bowel disease in Zhejiang, China. J Clin Nurs 2010; 19: 79-88.
9. Romberg-Camps MJL, Bol Y, Dagnelie PC, et al. Fatigue and health-related quality of life in in-flammatory bowel disease: results from a population-based study in the Netherlands: the IBDSouth Limburg Cohort. Inflamm Bowel Dis 2010; 16: 2137-2147.
10. Casellas F, Lopez-Vinancos J, Casado A, Malagelada JR. Factors affecting health related quality of life of patients with inflammatory bowel disease. Qual Life Res 2002; 11: 775-781.
11. Bernklev T, Jahnsen J, Lygren I, Henriksen M, Vatn M, Moum B. Health-related quality of life in patients with inflammatory bowel disease measured with the short form-36: psychometric assessments and a comparison with general population norms. Inflamm Bowel Dis 2005;11(10):909-918.
12. Haapamäki J, Turunen U, Roine RP, Färkkilä MA, Arkkila PE. Impact of demographic factors, medi-cation and symptoms on disease-specific quality of life in inflammatory bowel disease. QualLife Res 2009; 18(8): 961-969
13. Stjernman H, Tysk C, Almer S, Strom M, Hjortswang H. Worries and concerns in a large unselected cohort of patients with Crohn's disease. Scand J Gastroenterol 2010; 45: 696–706.
14. Dranga M, Dumitrescu G, Badea M, et al. The semi-quantitative calprotectin rapid test – it is useful in inflammatory bowel disease? Rev Med Chir Soc Med Nat Iasi 2012; 116(3): 761-765.
15. Mihai C, Cijevschi Prelipcean C, Pintilie I. Nutrition in inflammatory bowel diseases Rev Med Chir Soc Med Nat Iasi 2013; 117(3): 662-669.
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