LIVER METASTASIS OF A GASTROINTESTINAL STROMAL TUMOR OF LARGE BOWEL: CASE REPORT

Authors

  • Madalina PALAGHIA University of Medicine and Pharmacy "Grigore. T. Popa"- Iasi
  • Catalina MIHAI University of Medicine and Pharmacy "Grigore. T. Popa"- Iasi
  • M. DANCIU University of Medicine and Pharmacy "Grigore. T. Popa"- Iasi
  • E. TARCOVEANU ”Sf. Spiridon” Hospital Iasi
  • Felicia CRUMPEI ”Sf. Spiridon” Hospital Iasi
  • Cristina CIJEVSCHI-PRELIPCEAN University of Medicine and Pharmacy "Grigore. T. Popa"- Iasi

Abstract

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal malignancies of the digestive tract. We present the case of a 61-year-old male patient liver metastasis of a GIST with primary location at the level of sigmoid colon. Like in the majority of cases, the symptomatology in this patient has long been faint and when it became manifest, it was nonspecific. Imagery wise, the computer tomography (CT) scan was the most efficient, showing the origin of the tumor from large bowel, its dimensions, as well as the relations with the other abdominal viscera and the liver metastasis. Surgery in this patient was en-bloc, according to the principles of GIST and for the metastasis he followed treatment with Imatinib. The histological aspect is characterized by a proliferation of spindle cells positive for CD117 and CD34. Despite complete microscopic resection, the exhibit of liver metastasis remains an important relapse factor.

Author Biographies

  • Madalina PALAGHIA, University of Medicine and Pharmacy "Grigore. T. Popa"- Iasi

    Faculty of Medicine
    Department of Surgery

  • Catalina MIHAI, University of Medicine and Pharmacy "Grigore. T. Popa"- Iasi

    Faculty of Medicine
    Department of Medical Specialties (I)
    Institute of Gastroenterology and Hepathology Iasi

  • M. DANCIU, University of Medicine and Pharmacy "Grigore. T. Popa"- Iasi

    Faculty of Medicine
    Department of Morpho-Functional Sciences
    ”Sf. Spiridon” Hospital Iasi
    Department of Histopathology

  • E. TARCOVEANU, ”Sf. Spiridon” Hospital Iasi

    First Clinic of Surgery

  • Felicia CRUMPEI, ”Sf. Spiridon” Hospital Iasi

    Department of Radiology

  • Cristina CIJEVSCHI-PRELIPCEAN, University of Medicine and Pharmacy "Grigore. T. Popa"- Iasi

    Faculty of Medicine
    Department of Medical Specialties (I)
    Institute of Gastroenterology and Hepathology Iasi

References

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Additional Files

Published

2015-06-30

Issue

Vol. 119 No. 2 (2015): The Medical-Surgical Journal

Section

INTERNAL MEDICINE - PEDIATRICS

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