PALLIATIVE TREATMENT OF MALIGNANT ESOPHAGOPULMONARY FISTULAS WITH COVERED SELF - EXPANDABLE METALLIC STENTS (SEMSS). A SINGLE CENTER EXPERIENCE

Authors

  • V. PORUMB University of Medicine and Pharmacy”Grigore T. Popa” - Iași
  • A. COZORICI University of Medicine and Pharmacy”Grigore T. Popa” - Iași
  • Elena ANDRESE University of Medicine and Pharmacy”Grigore T. Popa” - Iași
  • S. MAKKAI-POPA University of Medicine and Pharmacy”Grigore T. Popa” - Iași
  • S. LUNCA University of Medicine and Pharmacy”Grigore T. Popa” - Iași
  • G. DIMOFTE University of Medicine and Pharmacy”Grigore T. Popa” - Iași

Abstract

Aim: The aim of our study was to determine the efficiency of SEMSs in patients with esophagopulmonary fistulas, regarding fistula closure,, enhancement of dysphagia scores and survival rates. Materials and Methods: Between January 2004 and June 2014, from a total of 133 patients who underwent stent placement procedures, 26 were diagnosed with esophagopulmonary fistulas. In 19 cases the fistulas were caused by esophageal carcinomas and in 7 cases by bronchogenic ones. 16 patients developed aspiration pneumonia, 3 lung abscess and 7 subclinical fistulas. Results: Complete fistula sealing occurred in 26 patients (100%). There were no immediate procedural complications except chest pain in 5 cases. After sealing of the fistulas and antibiotic treatment, pneumonia has regressed. After stent insertion, the dysphagic syndrome improved significantly (mean dysphagia scores decrease from 3.28 to 1.3 after stent insertion). The main goal of palliative therapy in patients with unresectable cancer and esophago-pulmonary fistulas is to close the fistulas, thus preventing the aspiration of saliva and food into the bronchus.  Other goals include amelioration of dysphagia symptoms, maintenance of oral intake and improvement of quality of life. Ultimately covered expandable metal stents may increase survival rate as compared with other therapies. Conclusions: The endoscopic placement of covered SEMSs is the treatment of choice for malignant esophago-pulmonary fistulas.

Author Biographies

  • V. PORUMB, University of Medicine and Pharmacy”Grigore T. Popa” - Iași

    Faculty of Medicine
    Department of Surgery

  • A. COZORICI, University of Medicine and Pharmacy”Grigore T. Popa” - Iași

    Faculty of Medicine
    Department of Surgery

  • Elena ANDRESE, University of Medicine and Pharmacy”Grigore T. Popa” - Iași

    Faculty of Medicine
    Department of Medical Specialties (II)

  • S. MAKKAI-POPA, University of Medicine and Pharmacy”Grigore T. Popa” - Iași

    Faculty of Medicine
    Department of Surgery

  • S. LUNCA, University of Medicine and Pharmacy”Grigore T. Popa” - Iași

    Faculty of Medicine
    Department of Surgery

  • G. DIMOFTE, University of Medicine and Pharmacy”Grigore T. Popa” - Iași

    Faculty of Medicine
    Department of Surgery

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Additional Files

Published

2015-06-30