ANTIOXIDANT AND PHYTOBIOLOGICAL STUDIES ON TWO ALLIUM CEPA L. EXTRACTS

Authors

  • Gabriela TATARINGA University of Medicine and Pharmacy“Grigore T. Popa”- Iasi
  • Cornelia MIRCEA University of Medicine and Pharmacy“Grigore T. Popa”- Iasi
  • Elvira GILLE “Stejarul” Biology Research Center, Piatra Neamt
  • Monica HANCIANU University of Medicine and Pharmacy“Grigore T. Popa”- Iasi
  • Alexandra JITAREANU University of Medicine and Pharmacy“Grigore T. Popa”- Iasi
  • Ana-Maria ZBANCIOC University of Medicine and Pharmacy“Grigore T. Popa”- Iasi
  • Catalina STAN University of Medicine and Pharmacy“Grigore T. Popa”- Iasi

Abstract

Aim: To investigate the antioxidant potential of two Allium cepa L. extracts. Material and methods: The antioxidant activity of the two extracts (encoded EC1 and EC2) was assessed using two methods: DPPH (2,2-diphenyl-1-picrylhydrazyl) scavenging capacity and determination of their reducing power; phytobiological studies were performed using grains of Triticum aestivum L., Falmura variety. Results and discussions: EC1 and EC2 extracts had a particular affinity for binding DPPH radicals. At equivalent concentrations, the reducing power of EC1extract was about 2 times higher compared to EC2, increasing with the concentration of the analyzed sample. The phytobiological study demonstrated that the investigated extracts had no cytotoxic and genotoxic potential.

Author Biographies

  • Gabriela TATARINGA, University of Medicine and Pharmacy“Grigore T. Popa”- Iasi

    Faculty of Pharmacy
    Department of Pharmaceutical Sciences I

  • Cornelia MIRCEA, University of Medicine and Pharmacy“Grigore T. Popa”- Iasi

    Faculty of Pharmacy
    Department of Pharmaceutical Sciences II

  • Monica HANCIANU, University of Medicine and Pharmacy“Grigore T. Popa”- Iasi

    Faculty of Pharmacy
    Department of Pharmaceutical Sciences II

  • Alexandra JITAREANU, University of Medicine and Pharmacy“Grigore T. Popa”- Iasi

    Faculty of Pharmacy
    Department of Pharmaceutical Sciences I

  • Ana-Maria ZBANCIOC, University of Medicine and Pharmacy“Grigore T. Popa”- Iasi

    Faculty of Pharmacy
    Department of Pharmaceutical Sciences I

  • Catalina STAN, University of Medicine and Pharmacy“Grigore T. Popa”- Iasi

    Faculty of Pharmacy
    Department of Pharmaceutical Sciences II

References

1. Block E. The organosulfur chemistry of the genus Allium – implications for the organic chemistry of sulfur. Angew Chem Int Ed (English) 1992; 31: 1135-1178.
2. Breu W. Allium cepa L.(onion). Part 1: chemistry and analysis. Phytomedicine 1996; 3: 293-306.
3. *** WHO monographs on selected medicinal plants. Vol. 1. Bulbus Allii Cepae. Geneva, World Health Organization, 1999, 5-15.
4. Lutomski J. Components and biological properties of some Allium species, Poznan, Institute of Me-dicinal Plants, 1987, 10–16.
5. Breu W, Dorsch W. Allium cepa L. (onion): Chemistry, analysis and pharmacology. In: Wagner H, Farnsworth NR editors. Economic Medicinal Plant Research, Vol 6. London, Academic Press, 1994, 115-147.
6. Griffiths G, Truemann L, Crowther T, Thomas B, Smith B. Onions - a global benefit to health. Phy-tother Res 2002; 16: 603-615.
7. Miron A, Aprotosoaie C, Hăncianu M, Tănăsescu V, Stănescu U. Evaluarea potenţialului antioxidant al produsului Menthae longifoliae folium şi influenţa tratamentului fitosanitar cu Topsin M asupra acestuia. Rev Med Chir Soc Med Nat Iasi 2004; 108(4): 832-838.
8. Shon MY, Choi SD, Kahng GG, Nam SH, Sung NJ. Antimutagenic, antioxidant and free radical scavenging activity of ethyl acetate extracts from white, yellow and red onions. Food Chem Toxicol 2004; 42: 659-666.
9. Popescu ML, Dinu M, Ursache DD. Contributions to the pharmacognostical study on Taraxacum officinale (L) Weber, Farmacia 2012; 58(5): 646-653.
10. Tătărîngă G, Hăncianu M, Aprotosoaie C, Poiată A, Vasilescu M, Gafiţanu E. Caracterizarea fitochimică şi microbiologică a unor extracte de Allium cepa L. în vederea includerii în dermopreparate. Rev Med Chir Soc Med Nat Iaşi 2005; 109 (3): 676-679.

Additional Files

Published

2015-06-30