VITAMIN D STATUS IN PATIENTS ADMITTED IN A CLINIC OF ENDOCRINOLOGY
Abstract
Vitamin D deficiency has been known as a global health problem and there were reported moderate to strong inverse associations between 25(OH) D concentrations and cardiovascular diseases, serum lipid concentrations, inflammation, glucose metabolism disorders, weight gain, infectious diseases, multiple sclerosis, mood disorders, declining cognitive function, impaired physical functioning, and all-cause mortality. In Romania there are only a few published reports on vitamin D status among adult population. Aim: To evaluate vitamin D status in 440 patients those were admitted in our clinic for various endocrine pathology. Material and method: Serum 25-hydroxy vitamin D was measured using chem-iluminescence assay. We categorized the vitamin D levels in 3 subgroups (deficiency, insufficiency and sufficiency). Results: In our study there was a high prevalence of both vitamin D deficiency and insufficiency, while optimal level was observed only in a very small number of patients. Conclusions: We demonstrated a high frequency of vitamin D deficiency in general population, especially in elderly and children. There are still many controversies regarding the optimal vitamin D status and the supplementation dosage, so long term large scale studies are needed regarding efficacy and safety.
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