PARAGANGLIOMA OF THE CAROTID BODY: CASE REPORT
Abstract
With an incidence of 0.03% of all tumors, carotid body tumors (CBTs) are extremely rare. We present the case of a 63 year old female patient with an asymptomatic right sided neck mass of 3 cm diameter. Doppler ultrasound and contrast-enhanced CT confirmed the clinical suspicion of carotid body tumor. The patient underwent complete surgical excision of the Shamblin group II tumor and an adjacent lymph node, without preoperative embolization. The histo-pathological examination diagnosed a benign CBT. There were no postoperative complications at 1 and 6 months follow-ups.
References
2. M.S. Sajid, G. Hamilton and D.M. Baker. A Multicenter Review of Carotid Body Tumour Manage-ment. Eur J Vasc Endovasc Surg 2007; 34: 127-130.
3. J. Fruhmann, J.B. Geigl, P. Konstantiniuk, T.U. Cohnert. Paraganglioma of the Carotid Body: Treat-ment Strategy and SDH-gene Mutations. Eur J Vasc Endovasc Surg 2013; 45: 431-436.
4. A. Kruger, P. Walker, W. Foster, J. Jenkins, N. Boyne, J. Jenkins. Important observations made man-aging carotid body tumors during a 25-year experience. J Vasc Surg 2010; 52: 1518-24.
5. I. Sen, E. Stephen, K. Malepathi, S Agarwal, N.K. Shyamkumar, S. Mammen. Neurological compli-cations in carotid body tumors: A 6-year single-center experience. J Vasc Surg 2012; 52: 64S–68S
6. A.D. da Gama, G. M. Cabral. Carotid body tumor presenting with carotid sinus syndrome. J Vasc Surg 2010; 52: 1668-70.
7. Borges LF, Heros RC, DeBrun G: Carotid body tumors managed with preoperative embolization. Report of two cases. J Neurosurg. 1983; 59: 867-870.
8. DuBois J, Kelly W, McMenamin P, et al.: Bilateral carotid body tumors managed with preoperative embolization: a case report and review. J Vasc Surg 1987; 5: 648-650.
9. AH Power, TC Bower, J Kasperbauer, et al.: Impact of preoperative embolization on outcomes of carotid body tumor resections. J Vasc Surg 2012; 56 (4): 979-989.
10. SK Kakkos, DJ Reddy, AD Shepard, et al.: Contemporary presentation and evolution of management of neck paragangliomas. J Vasc Surg 2009; 49 (6): 1365-1373.
11. Rinaldo A, Myssiorek D, Devaney KO, et al.: Which paragangliomas of the head and neck have a higher rate of malignancy?. Oral Oncol. 2004; 40: 458-460.
12. Lee JH, Barich F, Karnell LH, Robinson RA, Zhen WK, Gantz BJ, et al. National cancer data base report on malignant paragangliomas of the head and neck. Cancer 2002; 94: 730-737.
13. Shamblin WR, Re Mine WH, Sheps SG, Harrison Jr EG. Carotid body tumor. Clinicopathologic analysis of ninety cases. Am J Surg 1971; 122: 732-739
14. M.P.M. Paridaan, K.E.A. van der Bogt, J.C. Jansen, et al. Results from Craniocaudal Carotid Body Tumor Resection: Should It be the Standard Surgical Approach?. Eur J Vasc Endovasc Surg 2013; 46: 624-629.
15. Sajid MS, Hamilton G, Baker DM, et al.: A multicenter review of carotid body tumour management. Eur J Vasc Endovasc Surg. 2007; 34: 127-130.
16. J. R. Boyle, N. J. M. London, S. G. Tan, H. Thurston, P. R. F. Bell. Labile Blood Pressure after Bilat-eral Carotid Body Tumour Surgery. Eur J Vasc Endovasc Surg 1995; 9: 346-348.
17. A.S. Patel, B. Modarai, A. Freeman, T.S. Padayachee, P.R. Taylor. Unilateral Blindness Following Excision of a Carotid Body Tumour. Case presentation. EJVES extra Abstracts, available online: 7th of Sept, 2008.
18. S. Wiegand, I. Kureck, R. Chapot, A. M. Sesterhenn, S. Bien, J. A. Werner. Early side effects after embolization of a carotid body tumor using Onyx. J Vasc Surg 2010; 52:742-5.
19. J. Kohn, K. Raftery, E. Jewell. Familial carotid body tumors: A closer look. J Vasc Surg. 1999; 29 (4): 649-653.
20. Barber B, Ingram M, Kahn S, Bano G, Hodgson S, Vlahos I. Clinicoradiological manifestations of paraganglioma syndromes associated with succinyl dehydrogenase enzyme mutation. Insights Imaging 2011; 2: 431-438.
21. Patetsios P, Gable DR, Garret WV, Lamont JP, Kuhn JA, Shutze WP, et al. Management of carotid body paragangliomas and review of a 30-year experience. Ann Vasc Surg 2002; 16: 331-338.
22. Boedeker CC. Paragangliome und Paragangliomsyndrome. Laryngo-Rhino-Otol 2011; 90: S56-82.
23. De Toma G, Nicolanti V, Plocco M, Cavallaro G, Letizia C, Piccirillo G, et al. Baroreflex failure syndrome after bilateral excision of carotid body tumors: an underestimated problem. J Vasc Surg 2000; 31: 806-810.
24. Netterville JL, Reilly KM, Robertson D, Reiber ME, Armstrong WB, Childs P. Carotid body tumors: a review of 30 patients with 46 tumors. Laryngoscope 1995; 105: 115-126.

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