EPIDEMIOLOGICAL EVALUATION REGARDING THE ROLE OF CYSTIC FIBROSIS AS A RISK FACTOR FOR CHILD MALNUTRITION

Authors

  • Laura FLORESCU University of Medicine and Pharmacy “Grigore T. Popa”-Iasi
  • Dana Teodora Anton PADURARU University of Medicine and Pharmacy “Grigore T. Popa”-Iasi
  • Dana Elena MANDRU University Hospital “Sf. Maria” Iasi
  • Oana Raluca TEMNEANU Arcadia Hospital Iasi
  • F. D. PETRARIU University of Medicine and Pharmacy “Grigore T. Popa”-Iasi
  • Mioara Calipsoana MATEI University of Medicine and Pharmacy “Grigore T. Popa”-Iasi

Keywords:

CYSTIC FIBROSIS, MALNUTRITION, CHILDREN, NUTRITIONAL STATUS

Abstract

Cystic fibrosis (CF) is the most common monogenic autosomal recessive disorder with progressive chronic evolution which is potentially lethal. Poor growth is a characteristic of children suffering from cystic fibrosis. A poor nutritional status is an independent risk factor for inadequate survival in cystic fibrosis and is associated with disease complications. The appropriate nutritional management is an important part of the treatment so that the patient with cystic fibrosis can achieve normal growth and development and maintain the best possible health status. A balanced diet supplemented with snacks high in fat and calories is necessary to increase the caloric intake in children with cystic fibrosis. Children with cystic fibrosis have higher caloric needs than healthy children of the same age and sex. Malnutrition in CF is multifactorial. Cystic fibrosis is a complex multisystem disorder affecting mainly the gastrointestinal tract and respiratory system. In the past, malnutrition was an inevitable consequence of disease progression, leading to poor growth, impaired respiratory muscle function, decreased exercise tolerance and immunological impairment. A positive association between body weight and height and survival has been widely reported. The energy requirements of patients with CF vary widely and generally increase with age and disease severity. Cystic fibrosis remains a paediatric disorder which is often underdiagnosed but which, if therapeutically managed properly (by means of drug therapy as well as by appropriate physiotherapy techniques), can lead to improved quality of life and, thus, to a bigger life expectancy.

Author Biographies

  • Laura FLORESCU, University of Medicine and Pharmacy “Grigore T. Popa”-Iasi

    Faculty of Medicine
    Discipline of Infant Care

  • Dana Teodora Anton PADURARU, University of Medicine and Pharmacy “Grigore T. Popa”-Iasi

    Faculty of Medicine
    Discipline of Pediatrics

  • F. D. PETRARIU, University of Medicine and Pharmacy “Grigore T. Popa”-Iasi

    Faculty of Medicine
    Discipline of Hygiene-Environmental Health

  • Mioara Calipsoana MATEI, University of Medicine and Pharmacy “Grigore T. Popa”-Iasi

    Faculty of Medicine
    Discipline of Primary Health Care and Epidemiology

References

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Additional Files

Published

2018-05-08

Issue

Section

PREVENTIVE MEDICINE - LABORATORY