ANXIETY AND DEPRESSION IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE: AN OPEN AGENDA FOR RESEARCH
Keywords:
CHRONIC OBSTRUCTIVE PULMONARY DISEASE, DEPRESSION, ANXIETY.Abstract
Depression and anxiety are psychiatric conditions often associated with poor survival rate and impaired social functioning in chronic illnesses, like chronic obstructive pulmonary disease (COPD). COPD is a major cause of chronic morbidity and mortality, being nowadays the fourth leading cause of mortality worldwide and the burden of this disease is increasing as the population is ageing and it is continuously exposed to risk factors. Common mechanisms for explaining the association of anxiety, depression and COPD include cigarette smoke exposure, physical inactivity, social isolation, multiple episodes of dyspnea and chronic hypoxia. BODE index and MMRC dyspnea score could be associated with anxiety and depression in COPD patients and the screening usually implies administration of simple questionnaires. Therapeutic options for anxiety include serotonin-reuptake inhibitors, which decrease the perception of dyspnea, while newer antidepressants, such as venlafaxine, duloxetine and mirtazapine are particularly useful in depression, since they do not produce respiratory depression.
References
2. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. Fifth Edition (DSM V), United States: Amazon Publishing, 2013.
3. Hill K, Geist R, Goldstein RS. Anxiety and depression in end-stage COPD. Eur Respir J 2007; 31: 667-677.
4. Global Initiative for Chronic Obstructive Lung Disease (GOLD). Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease (Updated 2013), www.goldcopd.org
5. Emery CF, Huffman MJ, Busby AK. Behavioral Medicine in Pulmonary Rehabilitation. In: Pulmonary Rehabilitation. A Guideline to success 4th Ed, United States: Mosby Elsevier, 2009, 269-284.
6. Maurer J, Rebbapragada V, Borson S, et al. Anxiety and depression in COPD: current understanding, unanswered questions, and research needs. Chest 2008; 134: 43S-56S.
7. Hynninen KM, Breitve MH, Wiborg AB, et al. Psychological characteristics of patients with chronic obstructive pulmonary disease: a review. J Psychosom Res 2005; 59: 429-443.
8. Dowson CA, Kuijer RG, Mulder RT. Anxiety and self-management behaviour in chronic obstructive pulmonary disease: what has been learned? Chron Respir Dis 2004; 1: 213-220.
9. Vogle C, von Leupoldt A. Mental disorders in chronic obstructive pulmonary disease (COPD). Respir Med 2008; 102: 764-773.
10. van Ede L, Yzermans CJ, Brouwer HJ. Prevalence of depression in patients with chronic obstructive pulmonary disease: a systemic review. Thorax 1999; 54: 688-692.
11. Lacasse Y, Rousseau L, Maltais F. Prevalence of depressive symptoms and depression in patients with severe oxygen-dependent chronic obstructive pulmonary disease. J Cardiopulm Rehab 2001; 21: 80-86.
12. Yohannes AM, Baldwin RC, Connolly MJ. Depression and anxiety in elderly outpatients with chronic obstructive pulmonary disease: prevalence and validation of BASDEC screening questionnaire. Int J Geriatr Psychiatry 2000; 15: 1090-1096.
13. Schane R, Woodruff P, Dinno A, et al. Prevalence and risk factors of depressive symptoms in persons with chronic obstructive pulmonary disease. J Gen Intern Med 2008; 23(11): 1757- 1762.
14. Van Manen JG, Bindels PJE, Dekker FW, et al. Risk of depression in patients with chronic obstructive pulmonary disease and its determinants. Thorax 2002; 57: 412-416.
15. Cully J, Graham D, Stanley M. Quality of life in patients with chronic obstructive pulmonary disease and comorbid anxiety or depression. Psychosomatics 2006; 47: 312-319.
16. Almagro P, Calbo E, Ochoa A, et al. Mortality after hospitalization for COPD. Chest 2002; 121(5): 1441-1448.
17. Ng TP, Niti M, Tan WC, et al. Depressive symptoms and chronic obstructive pulmonary disease: effect on mortality, hospital readmission, symptom burden, functional status, and quality of life. Arch Intern Med 2007; 167(1): 60-67.
18. Gift AG, McCrone SH. Depression in patients with COPD. Heart Lung 1993; 22: 189-197.
19. Gudmundsson G, Gislason T, Jansons C, et al Depression, anxiety and health status after hospitaliza-tion for COPD: a multicentre study in the Nordic countries. Respir Med 2006; 100: 87-93.
20. Mikkelsen RL, Middelboe T, Pisinger C, et al. Anxiety and depression in patients with chronic ob-structive pulmonary disease (COPD). A review. Nord J Psychiatry 2004; 58: 65-70.
21. Regvat J, Zmitek A, Vegnuti M, et al. Anxiety and depression during hospital treatment of exacerbation of chronic obstructive pulmonary disease. J Int Med Res 2011; 39: 1028-1038.
22. Gudmundsson G, Gislason T, Jansons C, et al. Risk factors for rehospitalisation in COPD: role of health status, anxiety and depression. Eur Respir J 2005; 26: 414-419.
23. Abhishek J, Sermsak L. Psychiatric aspects of chronic lung disease. Curr Psychiatry Reports 2009; 11: 219-225.
24. Funk GC, Kirchheiner K, Burghuber OC, Hartl S. BODE index versus GOLD classification for ex-plaining anxious and depressive symptoms in patients with COPD – a cross-sectional study. Respir Res 2009; 10: 1. doi: 10.1186/1465-9921-10-1.
25. Celli BR, Cote CG, Marin JM, Casanova C, et al. The Body-Mass Index, Airflow Obstruction, Dysp-nea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease. NEJM 2004; 350: 1005-1012.
26. Horita N, Kaneko T, Shinkai M, et al. Depression in Japanese patients with Chronic Obstructive Pulmonary Disease: A cross-sectional study. Respir Care 2013; 58: 1196-1203.
27. Tetikkurt C, Ozdemir I, Tetikkurt S, et al. Anxiety and depression in COPD patients and correlation with sputum and BAL cytology. Multidisciplinary Respir Med 2011; 6(4): 226-231.
28. Gilty EJ, Nissinen A, Giamaoli S, et al. Low respiratory function increases the risk of depressive symptoms in later life in men. Psychosomatic Med 2010; 72: 53-60.
29. Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med 2001; 16(9): 606-613.
30. Borson S, Claypoole K, McDonald GJ. Depression and chronic obstructive pulmonary disease: Treatment trials. Semin Clin Neuropsychiatry 1998; 3: 115-130.
31. Nutt D, Ballenger JC, Lepine JP. Panic disorder. Clinical diagnosis, management and mechanisms. London: Martin Dunitz; 1999.
32. de Godoy DV, de Godoy RF. A randomized controlled trial of the effect of psychotherapy on anxiety and depression in chronic obstructive pulmonary disease. Arch Phys Med Rehab 2003; 84: 1154-1157.
33. Covino NA, Dirks JF, Kinsman RA, Seidel JV. Patterns of depression in chronic illness. Psychother Psychosom 1982; 37: 144-153.
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