PARKINSON’S DISEASE AND CAROTID INTIMA-MEDIA THICKNESS

Authors

  • D. ALEXA University of Medicine and Pharmacy “Grigore T. Popa”- Iasi
  • Aurora CONSTANTINESCU Neurology Clinic, Rehabilitation Hospital Iasi
  • D. BALTAG Neurology Clinic, Rehabilitation Hospital Iasi
  • B. IGNAT Neurology Clinic, Rehabilitation Hospital Iasi
  • D. N. PADURARU Neurology Clinic, Rehabilitation Hospital Iasi
  • O. BOLBOCEAN Neurology Clinic, Rehabilitation Hospital Iasi
  • C. D. POPESCU Neurology Clinic, Rehabilitation Hospital Iasi

Abstract

Reports about the impact of cerebrovascular disease (CVD) on clinical status in Parkinson’s disease (PD) are rather controversial. There have been a few studies and inconsistent results regarding the coincidence of Parkinson’s disease (PD) and atherosclerotic diseases, such as cerebrovascular disease. Carotid intima-media thickness (IMT) is a known marker for subclinical atherosclerosis. Aim: This study was done to investigate the carotid IMT between PD patients and controls. Material and methods: A total of 54 PD patients and 50 controls were examined. The duration of Parkinson’s disease, the severity of Parkinson’s disease (the Hoehn–Yahr stage) and carotid IMT were examined. Results: The mean Hoehn and Yahr stage was 2.78 (range 2-4). Duration of disease had a mean of 7.59 ± 0.85 years. The left CCA mean IMT was 0.900 ± 0.147 in Parkinson group and 0.828 ± 0.118 in control group (p=0.007). The right CCA mean IMT was 0.891 ± 0.176 mm in the Parkinson group and 0.860 ± 0.164 in control group (p=0.360). No relationship between the Hoehn and Yahr stages or the duration of PD with the IMT were found by the Pearson’s correlation test. Conclusions: The carotid IMT was higher in PD patients than in controls.

Author Biography

  • D. ALEXA, University of Medicine and Pharmacy “Grigore T. Popa”- Iasi

    Faculty of Medicine
    Ph.D. student

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Additional Files

Published

2018-05-14

Issue

Vol. 118 No. 1 (2014): The Medical-Surgical Journal

Section

INTERNAL MEDICINE - PEDIATRICS

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