CLINICAL FEATURES AND EVOLUTION OF ORGAN DYSFUNCTIONS IN SEPSIS

Authors

  • Codrina BEJAN University of Medicine and Pharmacy “Grigore T. Popa” – Iasi
  • Isabela LOGHIN University of Medicine and Pharmacy “Grigore T. Popa” – Iasi
  • F. ROSU University of Medicine and Pharmacy “Grigore T. Popa” – Iasi
  • G. DOROBAT University of Medicine and Pharmacy “Grigore T. Popa” – Iasi
  • Carmen-Mihaela DOROBAT University of Medicine and Pharmacy “Grigore T. Popa” – Iasi

Keywords:

DATA ANALYSIS, ORGAN FAILURE, SYSTEMIC INFLAMMATORY RESPONSE SYNDROME.

Abstract

In sepsis, the systemic inflammatory response is adapted to the etiologic agent and the increase in the level of mediators is associated with organ dysfunction. Currently, a rapid assessment of patient ability to develop an adequate immune response is not possible, the response mechanisms being similar in the context of different etiological agents. Aim: To find statistical arguments for the evolution of laboratory parameters in sepsis patients. Material and methods: This retrospective study included 90 patients diagnosed with sepsis. The clinical, etiological, and laboratory data, and Carmeli and APACHE II prognostic scores were analyzed. The data were processed using SPSS version 16.0. Results: The causative agents was identified in 16 cases; organ involvement and systemic response varied, and no statistical correlations were found between the inflammatory syndrome parameters and  Carmeli or APACHE II prognostic scores or identification of the causative agent. Conclusions:  Statistical correlations were found between maximum blood glucose levels and the presence of organ dysfunction in the studied sepsis patients. No correlations were found between sepsis severity and the presence of anemia or thrombocytopenia, or between fever syndrome and inflammatory syndrome.

Author Biographies

  • Codrina BEJAN, University of Medicine and Pharmacy “Grigore T. Popa” – Iasi

    Faculty of Medicine
    Discipline of Infectious Diseases

  • Isabela LOGHIN, University of Medicine and Pharmacy “Grigore T. Popa” – Iasi

    Faculty of Medicine
    Discipline of Infectious Diseases

  • F. ROSU, University of Medicine and Pharmacy “Grigore T. Popa” – Iasi

    Faculty of Medicine
    Discipline of Anesthesiology and Intensive Care

  • G. DOROBAT, University of Medicine and Pharmacy “Grigore T. Popa” – Iasi

    Faculty of Medicine
    Discipline of Anesthesiology and Intensive Care

  • Carmen-Mihaela DOROBAT, University of Medicine and Pharmacy “Grigore T. Popa” – Iasi

    Faculty of Medicine
    Discipline of Infectious Diseases

References

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Additional Files

Published

2018-05-14

Issue

Section

INTERNAL MEDICINE - PEDIATRICS