SUBACUTE FUNGAL ENDOCARDITIS DUE TO ACREMONIUM SPP: A CASE STUDY AND REVIEW OF THE LITERATURE

Authors

  • Carmen PANZARU University of Medicine and Pharmacy “Grigore T. Popa” - Iasi
  • Maria DAN Institute of Cardiovascular Diseases Iasi
  • M. O. BALASANIAN University of Medicine and Pharmacy “Grigore T. Popa” - Iasi
  • Geanina COADA Institute of Cardiovascular Diseases Iasi
  • Gr. TINICA Institute of Cardiovascular Diseases Iasi
  • E. R. DABIJA Institute of Cardiovascular Diseases Iasi

Keywords:

SUBACUTE FUNGAL ENDOCARDITIS, ACREMONIUM SPP, ECHOCARDIOGRAPHY.

Abstract

A 52 years old patient is hospitalized in June 2007 in the Cardiology Clinic of Cardiovascular Diseases Medical Institute in Iasi with suspected subacute infectious endocarditis. Echocardiography shows mobile vegetation on the pulmonary valve.  Acremonium spp is isolated from blood cultures after 2 weeks of incubation. The patient was treated with fluconazole, but died after 3 months due to renal failure.

Author Biographies

  • Carmen PANZARU, University of Medicine and Pharmacy “Grigore T. Popa” - Iasi

    Faculty of Medicine                                                                                                                                                Microbiology Discipline

  • M. O. BALASANIAN, University of Medicine and Pharmacy “Grigore T. Popa” - Iasi

    Faculty of Medicine                                                                                                                                                        Clinical Cardiology

References

1. Verweij PE, Brandt ME. Aspergillus, Fusarium and Other Opportunistic Moniliaceous Fungi.In: Patric R Murray editor. Manual of Clinical Microbioloy. Washington DC: ASM Press, 2007, 1802-1839.
2. Das S, Saha R, Dar SR et al. Acremonium species: a review of the etiological agents of emerging hyalohyphomycosis. Mycopathol 2010; 6: 361-375.
3. Guarro J, Gams W, Pujol I et al. Acremonium species: new emerging opportunists—in vitro antifungal susceptibilities and review. Clin Infect Dis 1997; 25: 1222–1229.
4. Guarro J, Palacio A, Gene J et al. A case of colonization of a prosthetic mitral valve by Acremonium strictum. Rev Iberoam Micol 2009; 26: 146–148.
5. Gupta A, Jain H, Lynde C et al. Prevalence and epidemiology of onychomycosis in patients visiting physicians’ offices: a multicenter Canadian survey of 15,000 patients. J Am Acad Dermatol 2010; 43: 244–248.
6. De Hoog GS, Guarro J, Gene J et al. Atlas of clinical fungi, 2nd ed. entraalbureau voor Schimmelcultures, Utrecht, Netherlands/ University Rovira i Virgili, Reus, Spain, 2000.
7. Heitmann L, Cometta A, Hurni M et al. Right-sided pacemaker-related endocarditis due to Acremonium species. Clin Infect Dis1997; 25: 158-160.
8. Endocarditis in dura mater prosthesis caused by Acremonium kiliense.Rev Inst Med Trop Sao Paulo 1981; 23:274-279.
9. Degeorges M, Heintz C, Valty J et al. Infectious endocarditis due to Listeria monocytogenes and Cephalosporium. Presse Med 1979; 30: 1377-1380.
10. Fincher RM, Fisher JF, Lovell RD el al. Infection due to the fungus Acremonium (cephalosporium). Medicine Baltimore 1991; 70:398-409.
11. Guarro J, Palacio A, Gené J el al. A case of colonization of a prosthetic mitral valve by Acremonium strictum. Rev Iberoam Micol 2009; 26: 146-148.
12. Mares M, Bazgan O. Diagnosticul de laborator al infectiilor produse de fungi. In: Buiuc D, Negut M: Tratat de microbiologie clinica, ed a 3-a, ed Medicala, Bucuresti, 2009: 953-1031.
13. Perdomo H, Sutton SA, García A et al. Spectrum of Clinically Relevant Acremonium Species in the United States. J Clin Microbiol 2011; 49: 243-256.
14. Felipe Francisco Tuon, Carolina Pozzi, Sergio Ricardo Penteado-Filho et al. Recurrent Acremonium infection in a kidney transplant patient treated with voriconazole: a case report. Rev Soc Brasileira MedTrop 2010; 43: 467-468.

Additional Files

Published

2018-05-16

Issue

Section

PREVENTIVE MEDICINE - LABORATORY